Activities of Vittorio PRODI related to 2011/0402(CNS)
Shadow opinions (1)
OPINION on the proposal for a Council decision on establishig the Specific Programme Implementing Horizon 2020 - The Framework Programme for Research and Innovation (2014-2020)
Amendments (13)
Amendment 82 #
Proposal for a decision
Annex 1 – point 3 – paragraph 4
Annex 1 – point 3 – paragraph 4
Cross-cutting action will also be vital in stimulating the interactions between the societal challenges and the enabling and industrial technologies needed to generate major technological breakthroughs. Examples of where such interactions may be developed are: the domain of eHealth, smart grids, intelligent transport systems, mainstreaming of climate actions, nanomedicine, more predictive and human-relevant tools for safety testing, risk assessment and health research, advanced materials for lightweight vehicles or the development of bio-based industrial processes and products. Strong synergies will therefore be fostered between the societal challenges and the development of generic enabling and industrial technologies. This will be explicitly taken into account in developing the multi-annual strategies and the priority setting for each of these specific objectives. It will require that stakeholders representing the different perspectives are fully involved in the implementation and in many cases, it will also require actions which bring together funding from the enabling and industrial technologies and the societal challenges concerned.
Amendment 94 #
Proposal for a decision
Annex 1 – part I – point 2.3 – paragraph 1
Annex 1 – part I – point 2.3 – paragraph 1
Research initiatives within this challenge are science-driven, large-scale, multidisciplinary and built around a visionary unifying goal. They tackle grand science and technology challenges requiring cooperation among a range of disciplines, communities and programmes, and often a paradigm shift in research approaches. The scientific advance should provide a strong and broad basis for future technological innovation and economic exploitation, as well as novel benefits for society. The overarching nature and magnitude implies that they can only be realised through a federated and sustained effort (in the order of 10 years duration).
Amendment 96 #
Proposal for a decision
Annex 1 – part II – point 1 – paragraph 9 – indent 3 a (new)
Annex 1 – part II – point 1 – paragraph 9 – indent 3 a (new)
- further development and application of more predictive and human-relevant tools for safety testing, risk assessment and health research;
Amendment 97 #
Proposal for a decision
Annex 1 – part II – point 1.1 – point 1.1.1 – paragraph 1
Annex 1 – part II – point 1.1 – point 1.1.1 – paragraph 1
The objective is to maintain and reinforce European leadership in technologies related to smart embedded components and systems. It also includes micro-nano-bio systems, high-throughput in-vitro tools, human-on-a-chip, virtual organs and other applications of computational systems biology, organic electronics, large area integration, underlying technologies for the Internet of Things (IoT) including platforms to support the delivery of advanced services, smart integrated systems, systems of systems and complex systems engineering.
Amendment 98 #
Proposal for a decision
Annex 1 – part II – point 1.4 – point 1.4.1 – paragraph 1
Annex 1 – part II – point 1.4 – point 1.4.1 – paragraph 1
The objective is to lay the foundations for the European industry to stay at the front line of innovation, also in the medium and long term. It encompasses the development of emerging tools such as synthetic biology, bioinformatics, systems biology and exploiting the convergence with other enabling technologies such as nanotechnology (e.g. bionanotechnology) and ICT (e.g. bioelectronics). These and other cutting-edge fields deserve appropriate measures in terms of research and development to facilitate effective transfer and implementation into new applications (drug delivery systems, biosensors, biochips, etc) and tools such as human-biology based experimental and computational methods to ensure safer consumer products.
Amendment 112 #
Proposal for a decision
Annex 1 – part III – point 1 – paragraph 1
Annex 1 – part III – point 1 – paragraph 1
Effective health promotion, supported by a robust evidence base, prevents disease, improves wellbeing and is cost effective. Health promotion and disease prevention also depend on an understanding of the determinants of health at a molecular level, on effective preventive tools, such as vaccines, on effective health and disease surveillance and preparedness, and on effective screening programmes.
Amendment 116 #
Proposal for a decision
Annex 1 – part III – point 1 – paragraph 2
Annex 1 – part III – point 1 – paragraph 2
Successful efforts to prevent, manage, treat and cure disease, disability and reduced functionality are underpinned by the fundamental understanding of their causes, processes (e.g. molecular pathways) and impacts, as well as factors underlying good health and wellbeing. Effective sharing of data and the linkage of these data with real- world large scale cohort studies is also essential, as is the translation of research findings into the clinic, in particular through the conduct of clinical trials.
Amendment 124 #
Proposal for a decision
Annex 1 – part III – point 1 – point 1.1 – paragraph 2
Annex 1 – part III – point 1 – point 1.1 – paragraph 2
In particular, a better understanding of the environment as a determinant of health will require integrated and human-relevant health research, safety testing and risk assessment, (ultimately replacing animal use), molecular biological, epidemiological and toxicological approaches to investigate health- environment relationships and elucidate pathways of human disease and toxicity, including studies of modes of action of chemicals, combined exposures to pollution and other environmental and climate related stressors, integrated toxicological testing as well as alternatives to animal testing. Innovative approaches to exposure assessment are needed using new- generation human-relevant biomarkers based on ‘omics’ and epigenetics, human biomonitoring, personal exposure assessments and modelling to understand combined, cumulative and emerging exposures, integrating socio-economic and behavioural factors. Improved links with environmental data using advanced information systems will be supported.
Amendment 128 #
Proposal for a decision
Annex 1 – part III – point 1 – point 1.2 – paragraph 1
Annex 1 – part III – point 1 – point 1.2 – paragraph 1
The development of screening programmes depends not only on the identification of early biomarkers of risk but also on key pathways and of disease onset, and their deployment depends on the testing and validation of screening methods and programmes. Identifying individuals and populations at high-risk of disease will allow personalised, stratified and collective strategies for efficacious and cost effective disease prevention to be developed.
Amendment 133 #
Proposal for a decision
Annex 1 – part III – point 1 – point 1.4 – paragraph 1
Annex 1 – part III – point 1 – point 1.4 – paragraph 1
There is a need for an improved understanding of health and disease, in people of all ages, so that new and better prevention measures, diagnosis and treatments can be developed. Interdisciplinary, translational research on the patho-physiology of disease using human biology-based tools and approaches is essential to improve the understanding of all aspects of disease processes, including a re- classification of normal variation and disease based on molecular data, and to validate and use research results in clinical applications.
Amendment 135 #
Proposal for a decision
Annex 1 – part III – point 1 – point 1.4 – paragraph 2
Annex 1 – part III – point 1 – point 1.4 – paragraph 2
Underpinning research will encompass and encourage development and use of new tools and approaches for the generation of biomedical data and include human biology-based ‘-omics’, high throughput and systems medicine approaches. These activities will demand close linkage between fundamental and clinical research and with long term cohort studies (and the corresponding research domains) as described above. Close links with research and medical infrastructures (databases, bio- banks etc.) will also be required, for standardisation, storage, sharing and access to data, which are all essential for maximising data utility and for stimulating more innovative and effective ways of analysing and combining datasets.
Amendment 148 #
Proposal for a decision
Annex 1 – part III – point 1 – point 1.12 – paragraph 1
Annex 1 – part III – point 1 – point 1.12 – paragraph 1
Multidisciplinary advanced and applied research and innovation with behavioural, gerontological, digital and other sciences is needed for cost effective user-friendly solutions for active, independent and assisted daily living (in the home, the workplace, etc.) for the ageing population and people with disabilities. This applies in a variety of settings and for technologies and systems and services enhancing quality of life and human functionality including mobility, smart personalised assistive technologies, service and social robotics, and ambient assistive environments without compromising relational capacities and quality of social interactions of patients and people receiving assistance. Research and innovation pilots to assess implementation and wide uptake of solutions will be supported.
Amendment 202 #
Proposal for a decision
Annex 1 – part IV – point 3.1 – paragraph 1 – point a
Annex 1 – part IV – point 3.1 – paragraph 1 – point a
(a) Assessment of risks and opportunities of new technologies and chemicals, including nanomaterials, in food, feed and consumer products; development, evaluation and validation of harmonised measurement, identification and quantification methods, integrated testing strategies and state-of- the-art non-animal experimental and computational tools for toxicological hazard and risk assessment, including alternative methods to animal testing for health and environmental effects; assessment of health effects of environmental pollution.